Wednesday, December 28, 2016

Fentanyl Outpaces Heroin as the Deadliest Drug on Long Island




Photo

Kristin Clarino, a toxicologist in the Suffolk County medical examiner’s office in Hauppauge, handling recently tested samples of fentanyl. The drug has killed at least 220 people on Long Island in 2016.CreditJohnny Milano for The New York Times

An anesthetic commonly used for surgery has surpassed heroin to become the deadliest drug on Long Island, killing at least 220 people there in 2016, according to medical examiners’ records.
The drug, fentanyl, is a synthetic opioid, which can be 100 times more potent than morphine.
The numbers from Long Island are part of a national pattern, as fentanyl fatalities have already surpassed those from heroin in other parts of the country, including New England, as its use has skyrocketed. Part of the reason for the increase is economic — because fentanyl can be manufactured in the lab, it is much cheaper and easier than cultivating heroin.
In New York City, more than 1,000 people are expected to die from drug overdoses this year — the first recorded four-digit death total in city history, according to statistics compiled by the Department of Health and Mental Hygiene. Nearly half of all unintentional drug overdose deaths in the city since July have involved fentanyl, the health department said.
The medical examiners of Long Island’s two counties, Nassau and Suffolk, compiled the new numbers. “Fentanyl has surpassed heroin as the most commonly detected drug in fatal opioid overdoses,” Dr. Michael J. Caplan, the Suffolk County medical examiner, said in a written statement about the statistics, which were obtained by The New York Times ahead of their release. “The influx of illicitly manufactured fentanyl from overseas is a nationwide issue that requires a multidisciplinary intervention from all levels of government.”
Continue reading the main story
Nationwide, recorded deaths from opioids surpassed 30,000 in 2015, according to data compiled by the Centers for Disease Control and Prevention. And overdoses caused by synthetic opioids like fentanyl increased by 72.2 percent in 2015 over 2014 — one of the deadliest year-over-year surges for any drug in United States history, the same data shows.
As recently as three years ago, few people outside the medical profession or law enforcement had even heard of fentanyl, which is legally prescribed in the form of transdermal patches or lozenges. But drug dealers have been lacing heroin with fentanyl for years, just to fill out the packets and save on the heroin — with or without the user’s knowledge.
At the same time, many drug users seek out fentanyl because it gives them a higher high and the thrill of using something so risky, although often they do not know exactly what they are shooting up.
In a statement responding to the overdose data, James J. Hunt, special agent in charge of the Drug Enforcement Administration’s New York Division, said that seizures of fentanyl had increased drastically in the last five years. “Not only are drug traffickers mixing it with heroin for street distribution,” he said, “but drug suppliers are sending it in bulk form for resellers to sell in pill form or in bulk powder.”
Prescription fentanyl is used to treat cancer pain and as an anesthetic for surgery. Even small amounts of it can be deadly. The drug is so powerful that law enforcement officers have to wear gloves when searching for it, as just a tiny bit can get into the skin and, depending on the amount, can be fatal.

Document: Suffolk County Opioid Deaths


“We’ve never seen as much of a drug this strong on the black market before,” said Jeffrey Sheridan, an Oyster Bay, N.Y., resident and addiction counselor whose 34-year-old nephew died from a fentanyl overdose on Staten Island in 2015. “It’s essentially the serial killer of drugs. It’s not something you can use for any kind of duration and survive.”
Fentanyl was the drug that killed Prince in April.
On Long Island, America’s most densely populated suburban region, opioids of all kinds killed at least 464 people in 2016, the medical examiners’ records show. Hundreds of additional drug overdose analyses are pending.
“Too many young people have fallen victim,” the Nassau County executive, Edward Mangano, said of the new data in a written statement. The Nassau County medical examiner, Dr. Tamara Bloom, did not comment on the new numbers.
In New York City, as of June, there were 184 fentanyl-related overdose deaths recorded — more than in all of 2015, health department records show. Since then, the number of fatal 2016 overdoses involving fentanyl has surged to about 500, according to the department data.
Fentanyl is increasingly being manufactured by Mexican drug cartels, according to the D.E.A., or is cooked up in labs in the United States. It is being sold by dealers in New York City and on Long Island, according to Mr. Hunt, the D.E.A. special agent.
Some users who purchase it believe they are actually buying prescription pain pills like oxycodone or hydrocodone, or heroin alone — drugs far less potent than fentanyl.
A user can fatally overdose within moments of snorting, injecting or swallowing the drug, authorities said.
One recovering addict said the drug is so powerful, he can no longer get high from heroin alone.
“Without the fentanyl, shooting heroin’s like shooting water — you build up a tolerance,” said Andrew Giordano, 26, of Prospect Heights, Brooklyn, who overdosed on a fentanyl-heroin mixture in February and is now in a treatment program.
Paramedics used a double dose of the lifesaving opioid antidote naloxone to revive him, he said.
Because the drug is so strong, they need to use about twice as much naloxone to save you, Mr. Giordano said. “Sometimes, it doesn’t work at all.”
Mr. Sheridan, the Long Island addiction counselor who lost his nephew to fentanyl, said the number of addicts using the drug in the city and suburbs was “astonishing.”
“It’s the scariest thing any of us who work in addiction recovery has seen,” he said.
Correction: December 28, 2016 
An earlier version of this article referred incorrectly to the proportion of drug overdose deaths in New York City that could be attributed to fentanyl. It is nearly half since July, not over half the number this year.

Monday, December 26, 2016

Panama Papers: What happened next?

Panama Papers: What happened next?

  • 26 December 2016
  •  
  • From the sectionWorld
Panama Papers

Panama Papers

This year saw the release of the biggest leak of documents in history, when the Panama Paperswere made public.
Eleven million documents were leaked from one of the world's most secretive companies, Panamanian law firm Mossack Fonseca. They revealed in detail how parts of the offshore industry work.
We asked you what stories over the last 12 months you wanted to hear more about and in response many of you asked - what happened as a result of the Panama Papers?
So we spoke to the journalists who brought the story to the world.

What was the immediate fallout?

The first casualty was the Prime Minister of Iceland, Sigmundur Gunnlaugsson, who resigned only days after the leaks showed he and his wife owned an offshore company that he had not declared on entering parliament.
Other world leaders, including Russian President Vladimir Putin and Pakistani Prime Minister Nawaz Sharif, addressed their countries to denounce the leaks and any allegations of being linked to money laundering.
In the UK, it caused political embarrassment for then-Prime Minister David Cameron, who admitted that his family had benefited from a legal offshore fund set up by his late father, Ian.
Authorities in the US and countries in Europe and Asia launched investigations into whether their rules were breached by those named in the leak.
Through it all, Mossack Fonseca has maintained it operates beyond reproach and has never been charged with wrongdoing.

How did it happen?

Bastian Obermayer and Frederik Obermaier are the two journalists at the heart of the leaks.
One night in 2014, Mr Obermayer was looking after his sick children when he received a message.
"Interested in data?" it said.
That data turned out to be millions of documents from Mossack Fonseca and the shell companies it sets up for wealthy people. The whistleblowers called themselves John Doe and their identity remains secret.
The journalists received hundreds of files a day and were soon overwhelmed with information from hundreds of thousands of offshore companies. They involved an international journalists' network and teams of reporters from around the world, including the BBC.

What do they think?

Eight months on from the publishing and broadcasting of the Panama Papers, what do they think it has achieved?
"We, together with the International Consortium for Investigative Journalists (ICIJ), did a follow-up," Mr Obermaier told the BBC.
"We found out in 79 countries around the world there have been inquiries, 6,500 taxpayers and companies are being investigated globally and Mossack Fonseca have had to close nine offices. They have even put down their sign boards at their headquarters in Panama."
Bastian Obermayer and Frederik Obermaier pose togetherImage copyrightGETTY IMAGES
Image captionBastian Obermayer and Frederik Obermaier
Mr Obermaier said the Panama Papers had shown how the offshore world could be used to help aid terrorism.
"It is striking for me that Europol found 3,469 probable matches between their own files and the Panama Papers - 116 between them on a project on Islamic terrorism alone."
Mr Obermayer agrees and said the leak had revealed that the offshore world was not only a place for rich people to avoid taxes. He said the Panama Papers showed the secrecy of shell companies could be used to hide criminal activity.
"I wasn't shocked that rich people use offshore to dodge taxes. I was shocked that there were so many crimes. I think the vast amount of offshore companies are used because someone wants to hide something."
Mr Obermayer argues there have been concrete changes as a result of the leak's publication.
"A lot has changed, in Germany. Our finance minister just introduced a new 'Panama Law' (requiring citizens to declare if they are using a shell company) and Panama itself is more open for change now.
"Some countries have announced registers for beneficial owners and others are also arguing for that for the first time ever.
"The pressure on tax havens is as high as never before and the Panama Papers have done that. They have directed the spotlight at the problem.
"But still, what hasn't changed is that the very industry that helps tax dodgers is still alive and kicking. They have huge influence, huge power, huge lobby groups. We don't see the end of offshore - but we do see that offshore is shrinking."

A potential solution?

Both journalists argue for a global register of beneficial owners to end tax secrecy. A beneficial owner is the person who has significant control of a company and its profits.
Richard Brooks, Private Eye journalist and author of The Great Tax Robbery is more pessimistic than the Panama Papers journalists.
"Whatever register you have, you would somehow have to police it," he said.
"You need law enforcement having sufficient resources to be able to investigate it. The serious money launderers and criminals would be able to make something up.
Mossack Fonesca signImage copyrightREUTERS
"The Panama Papers did give efforts to open up tax havens a bit of a boost, but it was not enough and there is evidence already of some backsliding. Britain's own tax havens, for example, will not open up the ownership of their shell companies to the public.
"We know that these territories are ill-equipped to police any international rules on information exchange imposed on them so, until they are completely transparent, we will be a long way from resolving the tax haven problem."
Attempts to establish transparency are being pushed back. For example, the EU has had to compromise on its plan for a public register of beneficial ownership after resistance from various member states.
The effectiveness of the measures being taken across the world as a result of the Panama Papers is still open to challenge.
Produced by Patrick Evans, UGC & Social News Hub

Doctors confirm 200-year-old diagnosis

Doctors confirm 200-year-old diagnosis

John HunterImage copyrightHUNTERIAN MUSEUM AT THE ROYAL COLLEGE OF SURGEONS
Doctors have confirmed a diagnosis made more than 200 years ago by one of medicine's most influential surgeons.
John Hunter had diagnosed a patient in 1786 with a "tumour as hard as bone".
Royal Marsden Hospital doctors analysed patient samples and case notes, which were preserved at the museum named after him - the Hunterian in London.
As well as confirming the diagnosis, the cancer team believe Mr Hunter's centuries-old samples may give clues as to how cancer is changing over time.
"It started out as a bit of fun exploration, but we were amazed by John Hunter's insight," Dr Christina Messiou told the BBC News website.
Mr Hunter became surgeon to King George III in 1776 and is one of the surgeons credited with moving the medical discipline from butchery to a science.
He's also rumoured to have given himself gonorrhoea as an experiment while writing a book about venereal diseases.
His huge medical collection is now housed at the Hunterian Museum at the Royal College of Surgeons.
It includes his colourful notes describing a man who arrived at St George's Hospital, in 1786, with a hard swelling on his lower thigh.
"It appeared to be a thickening of the bone, it was increasing very rapidly... On examining the diseased part, it was found to consist of a substance surrounding the lower part of the thigh bone, of the tumour kind, which seemed to originate from the bone itself."
Mr Hunter amputated the man's leg and he recovered briefly for four weeks.
"From this time he began to lose flesh and sink gradually, his breathing more and more difficult," the notes continued.
The patient died seven weeks after the operation and an autopsy discovered bony tumours had spread to his lungs, the lining of the heart and on the ribs.
Cancer spreading to the lungsImage copyrightCHRISTINA MESSIOU
Image captionBony growths had spread to the patient's lungs
More than 200 years later, the samples fell under the gaze of Dr Christina Messiou.
She said: "Just looking at the specimens, the diagnosis of osteosarcoma came very quickly to me and John Hunter's write up was amazingly astute and fits with what we know about the behaviour of the disease.
"The large volumes of new bone formation and the appearance of the primary tumour are really characteristic of osteosarcoma."
She went to get a second opinion from her colleagues at the Royal Marsden in central London.
And in an out-of-hours session at the hospital they used modern day scanning technology to confirm the centuries old diagnosis.
The team at the Royal Marsden so some out of hours scanning of the samplesImage copyrightCHRISTINA MESSIOU
Dr Messiou, whose speciality is sarcoma, told the BBC: "I think his diagnosis is really impressive and in fact his management of the patient followed similar principles to what we would have done in the modern day."
But she says the exciting stage of the research is still to come.
They are now going to compare more of Hunter's historical samples with contemporary tumours - both microscopically and genetically - to see if there are any differences.
Dr Messiou told the BBC: "It's a study of cancer evolution over 200 years and if we're honest we don't really know what we're going to find.
"But it would be interesting to see if we can link lifestyle risk factors with any differences that we see between historical and current cancers.
"So we've got big ambitions for the specimens."
Writing in the British Medical Journal, the Royal Marsden team apologised for delay in analysing the samples from 1786 and the obvious breach of cancer waiting times, but point out their hospital was not built until 1851.